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Thomas M Seed Selected Research

Radiation Injuries (Radiation Sickness)

7/2021Metabolomics-based predictive biomarkers of radiation injury and countermeasure efficacy: current status and future perspectives.
5/2020Alterations in Tissue Metabolite Profiles with Amifostine-Prophylaxed Mice Exposed to Gamma Radiation.
10/2019Metabolomic studies in tissues of mice treated with amifostine and exposed to gamma-radiation.
11/2014Tocols induce G-CSF and mobilise progenitors that mitigate radiation injury.
1/2014Progenitors mobilized by gamma-tocotrienol as an effective radiation countermeasure.
7/2012Amelioration of radiation-induced hematopoietic and gastrointestinal damage by Ex-RAD(R) in mice.
7/2011Mobilized progenitor cells as a bridging therapy for radiation casualties: a brief review of tocopherol succinate-based approaches.
1/2010Preclinical development of a bridging therapy for radiation casualties.
11/2003Genistein treatment protects mice from ionizing radiation injury.
6/2003Molecular and cellular biology of moderate-dose (1-10 Gy) radiation and potential mechanisms of radiation protection: report of a workshop at Bethesda, Maryland, December 17-18, 2001.

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Thomas M Seed Research Topics

Disease

14Acute Radiation Syndrome
03/2022 - 11/2014
10Radiation Injuries (Radiation Sickness)
07/2021 - 06/2003
4Wounds and Injuries (Trauma)
01/2021 - 05/2013
3Neoplasms (Cancer)
05/2020 - 02/2002
2Inflammation (Inflammations)
01/2021 - 12/2004
1Vomiting
01/2017
1Thrombosis (Thrombus)
07/2011
1Neutropenia
08/2006
1Drug-Related Side Effects and Adverse Reactions
11/2005
1Body Weight (Weight, Body)
11/2003
1Pancreatic Neoplasms (Pancreatic Cancer)
09/2003
1Shock
02/2003
1Weight Loss (Weight Reduction)
11/2002
1Carcinogenesis
02/2002
1Leukemia
02/2002

Drug/Important Bio-Agent (IBA)

11Pharmaceutical PreparationsIBA
01/2022 - 12/2004
4Amifostine (Ethyol)FDA LinkGeneric
11/2019 - 11/2005
4Granulocyte Colony-Stimulating Factor (G-CSF)IBA
01/2015 - 01/2010
3alpha-TocopherolFDA Link
06/2014 - 08/2006
2sodium salt (E)- 4- carboxystyryl- 4- chlorobenzylsulfoneIBA
01/2021 - 07/2012
2Investigational DrugsIBA
05/2020 - 01/2017
2Chemokine ReceptorsIBA
11/2014 - 06/2014
1romiplostimFDA Link
03/2022
1Biomarkers (Surrogate Marker)IBA
07/2021
1CBLB502IBA
01/2021
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2021
1CytokinesIBA
01/2021
1Radioisotopes (Radionuclides)IBA
01/2017
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
01/2015
1Colony-Stimulating Factors (Colony Stimulating Factor)IBA
01/2015
1plerixaforFDA Link
11/2014
1tocolIBA
11/2014
1DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
07/2012
1Oxygen (Dioxygen)IBA
07/2011
1polyethylene glycol 400IBA
11/2003
1FlavonoidsIBA
11/2003
1GenisteinIBA
11/2003
1Lipoxygenase InhibitorsIBA
09/2003
1MK-886IBA
09/2003
1CaspasesIBA
09/2003
1Dactinomycin (Actinomycin)FDA LinkGeneric
09/2003
1Biological ProductsIBA
06/2003
1Sulfhydryl Compounds (Thiols)IBA
02/2003
1EndotoxinsIBA
02/2003
1Messenger RNA (mRNA)IBA
02/2002
1Cobalt-60IBA
02/2002
1Oncogene Proteins (Oncogene Protein)IBA
02/2002

Therapy/Procedure

1Radiotherapy
05/2020
1Drug Therapy (Chemotherapy)
08/2006
1Injections
11/2002
1Oral Administration
11/2002